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1

A General and Mild Palladium-Catalyzed Domino Reaction for the Synthesis of 2H-Indazoles

Nis Halland, Marc Nazaré, Omar R'kyek, Jorge Alonso, Matthias Urmann, Andreas Lindenschmidt

Journal:

Angewandte Chemie

Year:

2009

Language:

english

File:

PDF, 289 KB

english, 2009

2

A Flexible, Palladium-Catalyzed Indole and Azaindole Synthesis by Direct Annulation of Chloroanilines and Chloroaminopyridines with Ketones

Marc Nazaré, Claudia Schneider, Andreas Lindenschmidt, David William Will

Journal:

Angewandte Chemie International Edition

Year:

2004

Language:

english

File:

PDF, 167 KB

english, 2004

3

Direct Experimental Evidence for Halogen-Aryl π Interactions in Solution from Molecular Torsion Balances

Sun, Han, Horatscheck, André, Martos, Vera, Bartetzko, Max, Uhrig, Ulrike, Lentz, Dieter, Schmieder, Peter, Nazaré, Marc

Journal:

Angewandte Chemie International Edition

Year:

2017

Language:

english

File:

PDF, 1.47 MB

english, 2017

4

A novel nitroreductase-enhanced MRI contrast agent and its potential application in bacterial imaging

Liu, Yun, Zhang, Leilei, Nazare, Marc, Yao, Qingqiang, Hu, Hai-Yu

Journal:

Acta Pharmaceutica Sinica B

Year:

2017

Language:

english

File:

PDF, 705 KB

english, 2017

5

Novel strategy for the preparation of 3-perfluoroalkylated-2 H -indazole derivatives

Abed, Hassen Bel, Weißing, Nils, Schoene, Jens, Paulus, Jannik, Sewald, Norbert, Nazaré, Marc

Journal:

Tetrahedron Letters

Year:

2018

Language:

english

File:

PDF, 660 KB

english, 2018

6

Synthese des (9S,18R)-Diastereomers von Cyclamenol A

Marc Nazaré, Herbert Waldmann

Journal:

Angewandte Chemie

Year:

2000

Language:

german

File:

PDF, 91 KB

german, 2000

7

Synthesis of the (9S,18R) Diastereomer of Cyclamenol A

Marc Nazaré, Herbert Waldmann

Journal:

Angewandte Chemie International Edition

Year:

2000

Language:

english

File:

PDF, 98 KB

english, 2000

8

Enantiospecific Synthesis of the (9S,18R)-Diastereomer of the Leukocyte Adhesion Inhibitor Cyclamenol A

Marc Nazaré, Herbert Waldmann

Journal:

Chemistry - A European Journal

Year:

2001

Language:

english

File:

PDF, 239 KB

english, 2001

9

Eine flexible, palladiumkatalysierte Indol- und Azaindolsynthese durch direkte Anellierung von Chloranilinen und Chloraminopyridinen mit Ketonen

Marc Nazaré, Claudia Schneider, Andreas Lindenschmidt, David William Will

Journal:

Angewandte Chemie

Year:

2004

Language:

german

File:

PDF, 168 KB

german, 2004

10

Evidence for CCl/CBr⋅⋅⋅π Interactions as an Important Contribution to Protein–Ligand Binding Affinity

Hans Matter, Marc Nazaré, Stefan Güssregen, David W. Will, Herman Schreuder, Armin Bauer, Matthias Urmann, Kurt Ritter, Michael Wagner, Volkmar Wehner

Journal:

Angewandte Chemie

Year:

2009

Language:

english

File:

PDF, 719 KB

english, 2009

11

Evidence for CCl/CBr⋅⋅⋅π Interactions as an Important Contribution to Protein–Ligand Binding Affinity

Hans Matter, Marc Nazaré, Stefan Güssregen, David W. Will, Herman Schreuder, Armin Bauer, Matthias Urmann, Kurt Ritter, Michael Wagner, Volkmar Wehner

Journal:

Angewandte Chemie International Edition

Year:

2009

Language:

english

File:

PDF, 719 KB

english, 2009

12

A General and Mild Palladium-Catalyzed Domino Reaction for the Synthesis of 2H-Indazoles

Nis Halland, Marc Nazaré, Omar R'kyek, Jorge Alonso, Matthias Urmann, Andreas Lindenschmidt

Journal:

Angewandte Chemie International Edition

Year:

2009

Language:

english

File:

PDF, 289 KB

english, 2009

13

Fragment Deconstruction of Small, Potent Factor Xa Inhibitors: Exploring the Superadditivity Energetics of Fragment Linking in Protein–Ligand Complexes

Dr. Marc Nazaré, Dr. Hans Matter, Dr. David W. Will, Dr. Michael Wagner, Dr. Matthias Urmann, Dr. Jörg Czech, Dr. Herman Schreuder, Dr. Armin Bauer, Dr. Kurt Ritter, Dr. Volkmar Wehner

Journal:

Angewandte Chemie International Edition

Year:

2012

Language:

english

File:

PDF, 1.12 MB

english, 2012

14

Inside Back Cover: Fragment Deconstruction of Small, Potent Factor Xa Inhibitors: Exploring the Superadditivity Energetics of Fragment Linking in Protein–Ligand Complexes (Angew. Chem. Int. Ed. 4/2012)

Dr. Marc Nazaré, Dr. Hans Matter, Dr. David W. Will, Dr. Michael Wagner, Dr. Matthias Urmann, Dr. Jörg Czech, Dr. Herman Schreuder, Dr. Armin Bauer, Dr. Kurt Ritter, Dr. Volkmar Wehner

Journal:

Angewandte Chemie International Edition

Year:

2012

File:

PDF, 927 KB

2012

15

A General Palladium-Catalyzed Sonogashira Coupling of Aryl and Heteroaryl Tosylates

Omar R'kyek, Nis Halland, Andreas Lindenschmidt, Jorge Alonso, Peter Lindemann, Matthias Urmann, Marc Nazaré

Journal:

Chemistry - A European Journal

Year:

2010

Language:

english

File:

PDF, 224 KB

english, 2010

16

ChemInform Abstract: Synthesis of the (9S,18R)-seco Acid of the Leukocyte Adhesion Inhibitor Cyclamenol A.

Marc Nazare, Herbert Waldmann

Journal:

Year:

2000

File:

PDF, 29 KB

2000

17

ChemInform Abstract: Synthesis of the (9S,18R) Diastereomer of Cyclamenol A.

Marc Nazare, Herbert Waldmann

Journal:

Year:

2000

File:

PDF, 30 KB

2000

18

ChemInform Abstract: Enantiospecific Synthesis of the (9S,18R)-Diastereomer of the Leukocyte Adhesion Inhibitor Cyclamenol A.

Marc Nazare, Herbert Waldmann

Journal:

Year:

2002

File:

PDF, 27 KB

2002

19

Factor Xa Inhibitors Based on a 2-Carboxyindole Scaffold: SAR of Neutral P1 Substituents.

Marc Nazare, et al. et al.

Journal:

Year:

2004

File:

PDF, 12 KB

2004

20

Novel Factor Xa Inhibitors Based on a 2-Carboxyindole Scaffold: SAR of P4 Substituents in Combination with a Neutral P1 Ligand.

Marc Nazare, et al. et al.

Journal:

Year:

2004

File:

PDF, 11 KB

2004

21

A Flexible, Palladium-Catalyzed Indole and Azaindole Synthesis by Direct Annulation of Chloroanilines and Chloroaminopyridines with Ketones.

Marc Nazare, Claudia Schneider, Andreas Lindenschmidt, David William Will

Journal:

Year:

2004

File:

PDF, 41 KB

2004

22

ChemInform Abstract: A General and Mild Palladium-Catalyzed Domino Reaction for the Synthesis of 2H-Indazoles.

Nis Halland, Marc Nazare, Omar R'kyek, Jorge Alonso, Matthias Urmann, Andreas Lindenschmidt

Journal:

Year:

2010

File:

PDF, 32 KB

2010

23

ChemInform Abstract: A General Palladium-Catalyzed Sonogashira Coupling of Aryl and Heteroaryl Tosylates.

Omar R'kyek, Nis Halland, Andreas Lindenschmidt, Jorge Alonso, Peter Lindemann, Matthias Urmann, Marc Nazare

Journal:

Year:

2011

File:

PDF, 41 KB

2011

24

ChemInform Abstract: A General and Mild Domino Approach to Substituted 1-Aminoindoles.

Nis Halland, Marc Nazare, Jorge Alonso, Omar R'kyek, Andreas Lindenschmidt

Journal:

Year:

2011

File:

PDF, 47 KB

2011

25

ChemInform Abstract: A Direct, Regioselective Palladium-Catalyzed Synthesis of N-Substituted Benzimidazoles and Imidazopyridines.

Jorge Alonso, Nis Halland, Marc Nazare, Omar R'kyek, Matthias Urmann, Andreas Lindenschmidt

Journal:

Year:

2011

File:

PDF, 48 KB

2011

26

A Direct, Regioselective Palladium-Catalyzed Synthesis of N-Substituted Benzimidazoles and Imidazopyridines

Jorge Alonso, Nis Halland, Marc Nazaré, Omar R'kyek, Matthias Urmann, Andreas Lindenschmidt

Journal:

European Journal of Organic Chemistry

Year:

2011

Language:

english

File:

PDF, 434 KB

english, 2011

27

Novel factor Xa inhibitors based on a benzoic acid scaffold and incorporating a neutral P1 ligand

Marc Nazaré, Hans Matter, Otmar Klingler, Fahad Al-Obeidi, Herman Schreuder, Gerhard Zoller, Jörg Czech, Martin Lorenz, Angela Dudda, Anusch Peyman, Hans Peter Nestler, Matthias Urmann, Armin Bauer, V

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2004

Language:

english

File:

PDF, 262 KB

english, 2004

28

Novel factor Xa inhibitors based on a 2-carboxyindole scaffold: SAR of P4 substituents in combination with a neutral P1 ligand

Marc Nazaré, Melanie Essrich, David W Will, Hans Matter, Kurt Ritter, Matthias Urmann, Armin Bauer, Herman Schreuder, Jörg Czech, Martin Lorenz, Volker Laux, Volkmar Wehner

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2004

Language:

english

File:

PDF, 265 KB

english, 2004

29

Factor Xa inhibitors based on a 2-carboxyindole scaffold: SAR of neutral P1 substituents

Marc Nazaré, Melanie Essrich, David W Will, Hans Matter, Kurt Ritter, Matthias Urmann, Armin Bauer, Herman Schreuder, Angela Dudda, Jörg Czech, Martin Lorenz, Volker Laux, Volkmar Wehner

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2004

Language:

english

File:

PDF, 271 KB

english, 2004

30

Synthesis of the (9S,18R)-seco acid of the leukocyte adhesion inhibitor cyclamenol A

Marc Nazaré, Herbert Waldmann

Journal:

Tetrahedron Letters

Year:

2000

Language:

english

File:

PDF, 103 KB

english, 2000

31

Efficient enantioselective synthesis of a β-hydroxyepoxide building block for the construction of macrocyclic natural products

Ulrich Schlede, Marc Nazaré, Herbert Waldmann

Journal:

Tetrahedron Letters

Year:

1998

Language:

english

File:

PDF, 168 KB

english, 1998

32

Fragment Deconstruction of Small, Potent Factor Xa Inhibitors: Exploring the Superadditivity Energetics of Fragment Linking in Protein–Ligand Complexes

Dr. Marc Nazaré, Dr. Hans Matter, Dr. David W. Will, Dr. Michael Wagner, Dr. Matthias Urmann, Dr. Jörg Czech, Dr. Herman Schreuder, Dr. Armin Bauer, Dr. Kurt Ritter, Dr. Volkmar Wehner

Journal:

Angewandte Chemie

Year:

2012

Language:

english

File:

PDF, 1.11 MB

english, 2012

33

Innenrücktitelbild: Fragment Deconstruction of Small, Potent Factor Xa Inhibitors: Exploring the Superadditivity Energetics of Fragment Linking in Protein–Ligand Complexes (Angew. Chem. 4/2012)

Dr. Marc Nazaré, Dr. Hans Matter, Dr. David W. Will, Dr. Michael Wagner, Dr. Matthias Urmann, Dr. Jörg Czech, Dr. Herman Schreuder, Dr. Armin Bauer, Dr. Kurt Ritter, Dr. Volkmar Wehner

Journal:

Angewandte Chemie

Year:

2012

File:

PDF, 912 KB

2012

34

Identification of High-Affinity P2Y 12 Antagonists Based on a Phenylpyrazole Glutamic Acid Piperazine Backbone

Zech, Gernot, Hessler, Gerhard, Evers, Andreas, Weiss, Tilo, Florian, Peter, Just, Melitta, Czech, Jörg, Czechtizky, Werngard, Görlitzer, Jochen, Ruf, Sven, Kohlmann, Markus, Nazaré, Marc

Journal:

Journal of Medicinal Chemistry

Year:

2012

Language:

english

File:

PDF, 2.79 MB

english, 2012

35

Selective non-lipid modulator of LPA5 activity in human platelets

Detlef H. Kozian, Andreas Evers, Peter Florian, Peter Wonerow, Sabrina Joho, Marc Nazare

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2012

Language:

english

File:

PDF, 1015 KB

english, 2012

36

Structural Requirements for Factor Xa Inhibition by 3-Oxybenzamides with Neutral P1 Substituents: Combining X-ray Crystallography, 3D-QSAR, and Tailored Scoring Functions

Matter, Hans, Will, David W., Nazaré,, Marc, Schreuder, Herman, Laux, Volker, Wehner, Volkmar

Journal:

Journal of Medicinal Chemistry

Year:

2005

Language:

english

File:

PDF, 1.61 MB

english, 2005

37

Autodeubiquitination Protects the Tumor Suppressor BAP1 from Cytoplasmic Sequestration Mediated by the Atypical Ubiquitin Ligase UBE2O

Mashtalir, Nazar, Daou, Salima, Barbour, Haithem, Sen, Nadine N., Gagnon, Jessica, Hammond-Martel, Ian, Dar, Haider H., Therrien, Marc, Affar, El Bachir

Journal:

Year:

2014

Language:

english

File:

PDF, 5.33 MB

english, 2014

38

Tractable synthesis of multipurpose screening compounds with under-represented molecular features for an open access screening platform

Wilde, Felix, Specker, Edgar, Neuenschwander, Martin, Nazaré, Marc, Bodtke, Anja, Link, Andreas

Journal:

Molecular Diversity

Year:

2014

Language:

english

File:

PDF, 542 KB

english, 2014

39

Probing the Subpockets of Factor Xa Reveals Two Binding Modes for Inhibitors Based on a 2-Carboxyindole Scaffold: A Study Combining Structure-Activity Relationship and X-ray Crystallography

Nazaré, Marc, Will, David W., Matter, Hans, Schreuder, Herman, Ritter, Kurt, Urmann, Matthias, Essrich, Melanie, Bauer, Armin, Wagner, Michael, Czech, Jörg, Lorenz, Martin, Laux, Volker, Wehner, Volkm

Journal:

Journal of Medicinal Chemistry

Year:

2005

Language:

english

File:

PDF, 644 KB

english, 2005

40

Discovery of N -[4-(1 H -Pyrazolo[3,4- b ]pyrazin-6-yl)-phenyl]-sulfonamides as Highly Active and Selective SGK1 Inhibitors

Halland, Nis, Schmidt, Friedemann, Weiss, Tilo, Saas, Joachim, Li, Ziyu, Czech, Jörg, Dreyer, Matthias, Hofmeister, Armin, Mertsch, Katharina, Dietz, Uwe, Strübing, Carsten, Nazare, Marc

Journal:

ACS Medicinal Chemistry Letters

Year:

2015

Language:

english

File:

PDF, 1.15 MB

english, 2015

41

Targeting Platelet G Protein-Coupled Receptors for Antithrombotic Therapy

Fälker, Knut, Nazare, Marc, Wonerow, Peter, Kozian, Detlef H.

Journal:

Drug Development Research

Year:

2013

Language:

english

File:

PDF, 164 KB

english, 2013

42

DOTAM Derivatives as Active Cartilage-Targeting Drug Carriers for the Treatment of Osteoarthritis

Hu, Hai-Yu, Lim, Ngee-Han, Ding-Pfennigdorff, Danping, Saas, Joachim, Wendt, K. Ulrich, Ritzeler, Olaf, Nagase, Hideaki, Plettenburg, Oliver, Schultz, Carsten, Nazare, Marc

Journal:

Bioconjugate Chemistry

Year:

2015

Language:

english

File:

PDF, 2.24 MB

english, 2015

43

SPIE Proceedings [SPIE International Conference on Optical Fibre Sensors (OFS24) - Curitiba, Brazil (Monday 28 September 2015)] 24th International Conference on Optical Fibre Sensors - A Bragg grating tunable filter based on temperature control system to demodulate a voltage sensor

Kalinowski, Hypolito J., Fabris, José Luís, Bock, Wojtek J., Ribeiro, Bessie A., Werneck, Marcelo M., de Nazaré, Fabio B. V., Gonçalves, Marceli N.

Year:

2015

Language:

english

File:

PDF, 341 KB

english, 2015

44

Modulation of Hexadecyl-LPA-Mediated Activation of Mast Cells and Microglia by a Chemical Probe for LPA5

Kozian, Detlef H., von Haeften, Elisabeth, Joho, Sabrina, Czechtizky, Werngard, Anumala, Upendra R., Roux, Pascale, Dudda, Angela, Evers, Andreas, Nazare, Marc

Journal:

Year:

2016

Language:

english

File:

PDF, 673 KB

english, 2016

45

Organophosphorus-mediated N–N bond formation: facile access to 3-amino-2H-indazoles

Bel Abed, Hassen, Schoene, Jens, Christmann, Mathias, Nazaré, Marc

Journal:

Organic & Biomolecular Chemistry

Year:

2016

Language:

english

File:

PDF, 1.19 MB

english, 2016

46

Temperature dependence of cross-effect dynamic nuclear polarization in rotating solids: advantages of elevated temperatures

Geiger, Michel-Andreas, Orwick-Rydmark, Marcella, Märker, Katharina, Franks, W. Trent, Akhmetzyanov, Dmitry, Stöppler, Daniel, Zinke, Maximilian, Specker, Edgar, Nazaré, Marc, Diehl, Anne, van Rossum,

Journal:

Physical Chemistry Chemical Physics

Year:

2016

Language:

english

File:

PDF, 4.10 MB

english, 2016

47

5-Aryl-2-(naphtha-1-yl)sulfonamide-thiazol-4(5H)-ones as clathrin inhibitors

Robertson, Mark James, horatscheck, Andre, Sauer, Samantha, von Kleist, Lisa, Baker, Jennifer R, Stahlschmidt, Wiebke, Nazare, Marc, Whiting, Ainslie, Chau, Ngoc, Robinson, Phillip J, Haucke, Volker,

Journal:

Organic & Biomolecular Chemistry

Year:

2016

Language:

english

File:

PDF, 1.08 MB

english, 2016

48

Modeling of Cotton Yields in the Amu Darya River Floodplains of Uzbekistan Integrating Multitemporal Remote Sensing and Minimum Field Data

Shi, Zhou, Ruecker, Gerd R., Mueller, Marc, Conrad, Christopher, Ibragimov, Nazar, Lamers, John P. A., Martius, Christopher, Strunz, Guenter, Dech, Stefan, Vlek, Paul L. G.

Journal:

Agronomy Journal

Year:

2007

Language:

english

File:

PDF, 286 KB

english, 2007

49

ChemInform Abstract: Organophosphorus-Mediated N-N Bond Formation: Facile Access to 3-Amino-2H-indazoles.

Bel Abed, Hassen, Schoene, Jens, Christmann, Mathias, Nazare, Marc

Journal:

Year:

2016

File:

PDF, 24 KB

2016

50

A straightforward approach to N -substituted-2 H -indazol-2-amines through reductive cyclization

Schoene, Jens, Bel Abed, Hassen, Christmann, Mathias, Nazaré, Marc

Journal:

Tetrahedron Letters

Year:

2017

Language:

english

File:

PDF, 357 KB

english, 2017

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